Collins, C.A., DiAntonio, A. (2004). Coordinating synaptic growth without being a nervous wreck.  Neuron 41(4): 489--491.

FBrf0175020

Note

The function and regulation of actin-cytoskeletal dynamics during synaptic growth is poorly understood. In this issue of Neuron, Coyle et al. report the identification of nervous wreck (nwk), a synapse-specific adaptor molecule in Drosophila that regulates synaptic growth and morphology via Wasp, a well-characterized mediator of actin dynamics.