Subject: Helping FlyBase: EDRC-SG14
Hi Dieter,
We are currently curating the abstracts for the 19th (Eger)
European Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
Subcellular expression of Drosophila PKD conforms to a role in the
regulation of secretory protein transport.
You mention a gene symbol that is new to FlyBase, PKD. Do you know
which of the Genome Project CG annotations your gene corresponds to?
All the CGs have corresponding gene records in FlyBase already and we
don't like to make duplicate records for what is actually the same gene
unless we can't avoid it. The CG symbols become synonyms when an
annotation is named with a more descriptive or functional name.
With best regards,
Rachel.
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Rachel Drysdale.
FlyBase (Cambridge),
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Subject: Re: Helping FlyBase: EDRC-SG14
Hi Rachel,
the PKD has the flybase annotation number CG7125. PKD was originally
classified as PKCm (human) or PKD1 (mouse). In vertebrates there are three
PKD known (PKD1 (PKCm), PKD2, PKD3 (PKCn). These genes has been in first
studies classified as new PKC's, however, the investigators found better
relationship to CAMP's. Therefore they called it PKD's (Protein Kinase D).
For a review see Rykx et al. 2003 FEBS Letters 546, 81-86.
I hope I could help you.
With best regards
Dieter
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Dieter Maier
University Hohenheim
Genetics (240)
Garbenstr, 30
70599 Stuttgart
Germany
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