Subject: Helping FlyBase: ADRC.06-60531
Dear Emily,
We are currently curating the abstracts for the upcoming 47th
(Houston) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
Eggless is a histone methyltransferase that mediates trimethylation of histone
H3 at lysine 9 in ovary germ cells.
You mention a gene symbol that is new to FlyBase, egg.  Do you know
which of the Genome Project CG annotations your gene corresponds to?
All the CGs have corresponding gene records in FlyBase already and we
don't like to make duplicate records for what is actually the same gene
unless we can't avoid it.  The CG symbols become synonyms when an
annotation is named with a more descriptive or functional name.
With best wishes,
Rachel.
Subject: eggless
Dear Rachel,
 My graduate student, Emily Clough, forwarded me your e-mail with the
questions about the eggless (egg) gene. The Drosophila genome project
actually has this region annotated as two genes: cg30422 and cg30426.
However, our results indicate that there is one transcription unit encoding
one protein, and that the two genes predicted by the Genome Project are
based on a failure to detect one of the egg introns (thereby introducing a
stop codon that is not actually present in the egg transcript). Our
evidence is based on sequence analysis of several overlapping embryo and
ovary cDNAs.
.
Best,
Tulle
Tulle Hazelrigg
Dept. of Biological Sciences
Columbia University
602 Fairchild, 1212 Amsterdam Ave.
New York, NY  10027