Brittle, A.L., Ohkura, H. (2005). Centrosome Maturation: Aurora Lights the Way to the Poles.  Curr. Biol. 15(21): R880--R882.

FBrf0191747

Note

The centrosome is the main microtubule organising centre in the cell. During mitosis, centrosomes dramatically increase microtubule nucleating activity, enabling them to form a mitotic spindle. Recent studies show that Aurora A kinase promotes microtubule assembly from centrosomes through the phosphorylation of the conserved centrosomal protein TACC.