Stowers, L., Logan, D.W. (2008). LUSH shapes up for a starring role in olfaction.  Cell 133(7): 1137--1139.

FBrf0205518

Note

In the fruit fly Drosophila, odorant-binding proteins are secreted into the fluid that bathes olfactory neurons. Laughlin et al. (2008) now challenge the assumption that the odorant-binding protein LUSH passively transports its pheromone to a specific olfactory receptor. Instead, LUSH undergoes a conformational change upon pheromone binding that is sufficient for neuronal activation.