FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Citation
Nijhout, H.F. (2008). Size matters (but so does time), and it's OK to be different.  Dev. Cell 15(4): 491--492.
FlyBase ID
FBrf0205972
Publication Type
Note
Abstract
In this issue of Developmental Cell, Layalle et al. reveal new insights into how nutrition controls body size in Drosophila. Nutrition specifically affects the activity of target of rapamycin (TOR) in the prothoracic gland. Under low-nutrition conditions, TOR suppresses ecdysone secretion--which otherwise terminates larval development--thereby prolonging growth and allowing larvae to still attain a near-normal body size.
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PubMed Central ID
Related Publication(s)
Research paper

The TOR pathway couples nutrition and developmental timing in Drosophila.
Layalle et al., 2008, Dev. Cell 15(4): 568--577 [FBrf0206030]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Cell
    Title
    Developmental Cell
    Publication Year
    2001-
    ISBN/ISSN
    1534-5807 1878-1551
    Data From Reference