FB2026_03 , released September 17, 2026
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Citation
Korenjak, M., Dyson, N. (2008). A vanishing act, explained.  Dev. Cell 15(6): 793--794.
FlyBase ID
FBrf0206506
Publication Type
Note
Abstract
In a paper in this issue of Developmental Cell, Shibutani et al. (2008) uncover the mechanism that underlies tightly regulated S-phase degradation of Drosophila E2F1 during development. They show that dE2F1 is degraded by the Cul4(Cdt2) ubiquitin ligase in a manner that resembles the DNA replication-dependent turnover of Cdt1.
PubMed ID
19081066
PubMed Central ID
DOI
10.1016/j.devcel.2008.11.007
Related Publication(s)
Research paper

Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase.
Shibutani et al., 2008, Dev. Cell 15(6): 890--900 [FBrf0206613]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Cell
    Title
    Developmental Cell
    Publication Year
    2001-
    ISBN/ISSN
    1534-5807 1878-1551
    Data From Reference