Rauzi, M., Lecuit, T. (2009). Closing in on mechanisms of tissue morphogenesis.  Cell 137(7): 1183--1185.

FBrf0208262

Note

It remains largely unknown how large-scale tissue movements during development emerge from the interplay of different tensile forces associated with actomyosin networks. Solon et al. (2009) now report that a ratchet-like mechanism drives the movement of epithelial sheets during dorsal closure in embryos of the fruit fly Drosophila.