Wang, C., Girton, J., Johansen, J., Johansen, K.M. (2011). A Balance Between Euchromatic (JIL-1) and Heterochromatic [SU(VAR)2-5 and SU(VAR)3-9] Factors Regulates Position-Effect Variegation in Drosophila. Genetics 188(3): 745--748.
FlyBase ID
FBrf0214243
Publication Type
Research paper
Abstract
In this study, we show that the haplo-enhancer effect of JIL-1 has the ability to counterbalance the haplo-suppressor effect of both Su(var)3-9 and Su(var)2-5 on position-effect variegation, providing evidence that a finely tuned balance between the levels of JIL-1 and the major heterochromatin components contributes to the regulation of gene expression.
