Schwartz, Y.B., Pirrotta, V. (2009). A little bit of sugar makes polycomb better.  J. Mol. Cell. Biol. 1(1): 11--12.

FBrf0215114

Note

Transcriptional repression by Polycomb group (PcG) proteins is now sweetened by the discovery of the essential role of O-GlcNAc glycosylation in the process. PcG protein polyhomeotic may be the key target, but alternative or additional functions including repression of transcription through glycosylation of the C-terminal domain of RNA polymerase II are also possible.