FB2026_03 , released September 17, 2026
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Citation
Schejter, E.D. (2009). Delta traffic takes a sh-Arp turn.  Nat. Cell Biol. 11(7): 791--793.
FlyBase ID
FBrf0215157
Publication Type
Note
Abstract
In the Notch pathway, the transmembrane ligand Delta is internalized and then re-established on the surface of signal-sending cells to allow the productive binding and activation of the Notch receptor on neighbouring cells. Arp2/3-dependent actin polymerization directs Delta trafficking through this circuit.
PubMed ID
19568264
PubMed Central ID
DOI
10.1038/ncb0709-791
Related Publication(s)
Research paper

The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors.
Rajan et al., 2009, Nat. Cell Biol. 11(7): 815--824 [FBrf0208249]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Cell Biol.
    Title
    Nature Cell Biology
    Publication Year
    1999-
    ISBN/ISSN
    1465-7392 1476-4679
    Data From Reference