FB2026_03 , released September 17, 2026
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Citation
Yan, D., Lin, X. (2008). Opposing roles for glypicans in Hedgehog signalling.  Nat. Cell Biol. 10(7): 761--763.
FlyBase ID
FBrf0215640
Publication Type
Note
Abstract
Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite effects of glypicans on Hedgehog signalling and show how their core protein domains and GPI anchor contribute to their versatile biological functions.
PubMed ID
18591969
PubMed Central ID
DOI
10.1038/ncb0708-761
Related Publication(s)
Research paper

Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis.
Gallet et al., 2008, Dev. Cell 14(5): 712--725 [FBrf0204921]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Cell Biol.
    Title
    Nature Cell Biology
    Publication Year
    1999-
    ISBN/ISSN
    1465-7392 1476-4679
    Data From Reference