FB2026_02 , released June 18, 2026
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Citation
Birman, S. (2008). Neurodegeneration: RNA turns number one suspect in polyglutamine diseases.  Curr. Biol. 18(15): R659--RR661.
FlyBase ID
FBrf0215760
Publication Type
Note
Abstract
Polyglutamine expansion diseases are triggered by the accumulation of toxic proteins. A new study reports that RNA molecules containing long CAG repeats can also be toxic to neurons and may play a significant role in pathogenesis.
PubMed ID
18682207
PubMed Central ID
DOI
10.1016/j.cub.2008.06.023
Related Publication(s)
Research paper

RNA toxicity is a component of ataxin-3 degeneration in Drosophila.
Li et al., 2008, Nature 453(7198): 1107--1111 [FBrf0205158]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference