FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Giebel, B., Wodarz, A. (2012). Notch signaling: numb makes the difference.  Curr. Biol. 22(4): R133--R135.
FlyBase ID
FBrf0217603
Publication Type
Note
Abstract
During Drosophila sensory organ precursor cell development, Numb segregates asymmetrically and functions as a cell fate determinant. Recent work now demonstrates in vivo that Numb inactivates Notch by promoting its endocytosis.
PubMed ID
22361152
PubMed Central ID
DOI
10.1016/j.cub.2012.01.006
Related Publication(s)
Research paper

Endocytosis by Numb breaks Notch symmetry at cytokinesis.
Couturier et al., 2012, Nat. Cell Biol. 14(2): 131--139 [FBrf0217937]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference