FB2026_03 , released September 17, 2026
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Citation
Ferrari, F., Jung, Y.L., Kharchenko, P.V., Plachetka, A., Alekseyenko, A.A., Kuroda, M.I., Park, P.J. (2013). Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters".  Science 340(6130): 273.
FlyBase ID
FBrf0221365
Publication Type
Note
Abstract
Conrad et al. (Reports, 10 August 2012, p. 742) reported a doubling of RNA polymerase II (Pol II) occupancy at X-linked promoters to support 5' recruitment as the key mechanism for dosage compensation in Drosophila. However, they employed an erroneous data-processing step, overestimating Pol II differences. Reanalysis of the data fails to support the authors' model for dosage compensation.
PubMed ID
23599463
PubMed Central ID
PMC3665607 (PMC) (EuropePMC)
DOI
10.1126/science.1231815
Related Publication(s)
Research paper

Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters.
Conrad et al., 2012, Science 337(6095): 742--746 [FBrf0219130]

Note

Response to Comments on "Drosophila Dosage Compensation Involves Enhanced Pol II Recruitment to Male X-Linked Promoters".
Vaquerizas et al., 2013, Science 340(6130): 273 [FBrf0221535]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075 1095-9203
    Data From Reference