Dempsey, D.R., Jeffries, K.A., Anderson, R.L., Carpenter, A.M., Rodriquez Opsina, S., Merkler, D.J. (2014). Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins. FEBS Lett. 588(4): 594--599.
FlyBase ID
FBrf0224043
Publication Type
Research paper
Abstract
Arylalkylamine N-acyltransferase-like 2(2) (AANATL2) from Drosophila melanogaster was expressed and shown to catalyze the formation of long-chain N-acylserotonins and N-acydopamines. Subsequent identification of endogenous amounts of N-acylserotonins and colocalization of these fatty acid amides and AANATL2 transcripts gives supporting evidence that AANATL2 has a role in the biosynthetic formation of these important cell signalling lipids.
