Bartok, O., Kyriacou, C.P., Levine, J., Sehgal, A., Kadener, S. (2013). Adaptation of molecular circadian clockwork to environmental changes: a role for alternative splicing and miRNAs. Proc. Biol. Sci. 280(1765): 20130011.
FlyBase ID
FBrf0224282
Publication Type
Review
Abstract
Circadian (24 h) clocks provide a source of internal timing in most living organisms. These clocks keep time by using complex transcriptional/post-translational feedback loops that are strikingly resilient to changes in environmental conditions. In the last few years, interest has increased in the role of post-transcriptional regulation of circadian clock components. Post-transcriptional control plays a prominent role in modulating rapid responses of the circadian system to environmental changes, including light, temperature and general stress and will be the focus of this review.
