FB2026_02 , released June 18, 2026
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Citation
Sapetschnig, A., Miska, E.A. (2014). Getting a Grip on piRNA Cluster Transcription.  Cell 157(6): 1253--1254.
FlyBase ID
FBrf0225341
Publication Type
Note
Abstract
The generation of piRNAs from long primary transcripts requires specialized factors that distinguish these precursors from canonical RNA polymerase II transcripts. Mohn et al. and Zhang et al. provide evidence that in Drosophila melanogaster noncanonical transcription coupled with splicing inhibition differentiates piRNA precursors from mRNAs and ensures their correct processing.
PubMed ID
24906143
PubMed Central ID
PMC4053829 (PMC) (EuropePMC)
DOI
10.1016/j.cell.2014.05.022
Related Publication(s)
Research paper

The Rhino-Deadlock-Cutoff Complex Licenses Noncanonical Transcription of Dual-Strand piRNA Clusters in Drosophila.
Mohn et al., 2014, Cell 157(6): 1364--1379 [FBrf0225218]

The HP1 Homolog Rhino Anchors a Nuclear Complex that Suppresses piRNA Precursor Splicing.
Zhang et al., 2014, Cell 157(6): 1353--1363 [FBrf0225219]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference