Tirmarche, S., Kimura, S., Sapey-Triomphe, L., Sullivan, W., Landmann, F., Loppin, B. (2014). Drosophila Protamine-Like Mst35Ba and Mst35Bb Are Required for Proper Sperm Nuclear Morphology but Are Dispensable for Male Fertility.  G3 (Bethesda) 4(11): 2241--2245.

FBrf0226721

Research paper

During spermiogenesis, histones are massively replaced with protamines. A previous report showed that Drosophila males homozygous for a genomic deletion covering several genes including the protamine-like genes Mst35Ba/b are surprisingly fertile. Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility.

PMC4232549 (PMC) (EuropePMC)