FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Clemente-Ruiz, M., Milán, M. (2015). Epithelial Cell Division: Keeping Aneuploidy Levels in Check.  Curr. Biol. 25(7): R275--R277.
FlyBase ID
FBrf0228027
Publication Type
Note
Abstract
Aneuploidy is deleterious at the cellular and organismal level and can promote tumorigenesis. Two new studies in Drosophila imaginal discs underscore the cellular and tissue-wide mechanisms that prevent the accumulation of aneuploid cells in symmetrically dividing epithelial tissues upon changes in centrosome number.
PubMed ID
PubMed Central ID
Related Publication(s)
Research paper

Acentrosomal Drosophila epithelial cells exhibit abnormal cell division, leading to cell death and compensatory proliferation.
Poulton et al., 2014, Dev. Cell 30(6): 731--745 [FBrf0226397]

Moesin is a major regulator of centrosome behavior in epithelial cells with extra centrosomes.
Sabino et al., 2015, Curr. Biol. 25(7): 879--889 [FBrf0227963]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference