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Citation
Obermayer, B., Rajewsky, N. (2014). Mixed messages: Re-initiation factors regulate translation of animal mRNAs.  Cell Res. 24(12): 1383--1384.
FlyBase ID
FBrf0228476
Publication Type
Note
Abstract
When ribosomes encounter upstream open reading frames (uORFs) during scanning of the 5' untranslated region (5' UTR), translation of the downstream ORF requires re-initiation. In a recent paper in Nature, Schleich et al. describe metazoan factors which specifically promote re-initiation.
PubMed ID
25145358
PubMed Central ID
PMC4260343 (PMC) (EuropePMC)
DOI
10.1038/cr.2014.114
Related Publication(s)
Research paper

DENR-MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth.
Schleich et al., 2014, Nature 512(7513): 208--212 [FBrf0226143]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell Res.
    Title
    Cell Research
    Publication Year
    1990
    ISBN/ISSN
    1001-0602
    Data From Reference