FB2026_02 , released June 18, 2026
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Citation
Amrein, H. (2014). An expression system for Gustatory receptors-and why it failed.  Fly 8(4): 232--233.
FlyBase ID
FBrf0228947
Publication Type
Note
Abstract
A recent paper by the Dahankuar laboratory suggested that single Drosophila sugar receptors proteins accurately mediate sugar detection when ectopically expressed in olfactory neurons of the antenna. These findings contra-dict numerous previously published electrophysiological and behavioral investigations, which all point towards heteromultimeric sugar taste receptors. Here, I provide some explanation why this "pseudo-heterologous" expression system may have led to this misleading conclusion.
PubMed ID
PubMed Central ID
PMC4594606 (PMC) (EuropePMC)
Related Publication(s)
Research paper

Detection of sweet tastants by a conserved group of insect gustatory receptors.
Freeman et al., 2014, Proc. Natl. Acad. Sci. U.S.A. 111(4): 1598--1603 [FBrf0224008]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Fly
    Title
    Fly
    Publication Year
    2007-
    ISBN/ISSN
    1933-6934 1933-6942
    Data From Reference