FB2026_03 , released September 17, 2026
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Citation
Bier, E., Nizet, V. (2015). Hedgehog: linking uracil to innate defense.  Cell Host Microbe 17(2): 146--148.
FlyBase ID
FBrf0230370
Publication Type
Note
Abstract
The ability of the gut epithelium to defend against pathogens while tolerating harmless commensal organisms remains an important puzzle. In this issue of Cell Host & Microbe, Lee et al. (2015) reveal how pathogen-secreted uracil acts at two steps to induce ROS via the Hedgehog pathway.
PubMed ID
25674980
PubMed Central ID
DOI
10.1016/j.chom.2015.01.010
Related Publication(s)
Research paper

Bacterial Uracil Modulates Drosophila DUOX-Dependent Gut Immunity via Hedgehog-Induced Signaling Endosomes.
Lee et al., 2015, Cell Host Microbe 17(2): 191--204 [FBrf0227504]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell Host Microbe
    Title
    Cell Host & Microbe
    Publication Year
    2007--
    ISBN/ISSN
    1931-3128 1934-6069
    Data From Reference