Dziarski, R., Gupta, D. (2018). A Balancing Act: PGRPs Preserve and Protect.  Cell Host Microbe 23(2): 149--151.

FBrf0238166

Note

How does the immune system maintain a balance between preserving a beneficial microbiome and protecting against pathogens while also inducing effective, yet not damaging, responses? In this issue of Cell Host & Microbe, Charroux et al. (2018) reveal that, in Drosophila, this task is performed by three isoforms of PGRP-LB, a peptidoglycan-hydrolyzing amidase.