FB2026_03 , released September 17, 2026
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Citation
Shears, S.B., Hayakawa, Y. (2018). The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?  Cytokine 110(): 298--300.
FlyBase ID
FBrf0239847
Publication Type
Note
Abstract
Our laboratories have determined that the Drosophila cytokine, Growth-blocking peptide (GBP), mediates its biological effects through the Mthl10 G-protein coupled receptor. In this Cytokine Stimulus, we discuss the functional plasticity of the GBP/Mthl10 axis, and we propose that conserved components of this regulatory network may be relevant to human health.
PubMed ID
29456061
PubMed Central ID
PMC6093804 (PMC) (EuropePMC)
DOI
10.1016/j.cyto.2018.02.016
Related Publication(s)
Research paper

Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress.
Sung et al., 2017, Proc. Natl. Acad. Sci. U.S.A. 114(52): 13786--13791 [FBrf0237648]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cytokine
    Title
    Cytokine
    ISBN/ISSN
    1043-4666 1096-0023
    Data From Reference