FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Reference
Citation
Sweeney, H.L. (2018). Too much of a good thing.  eLife 7(): e41178.
FlyBase ID
FBrf0240215
Publication Type
Note
Abstract
A mutation that causes heart disease in humans increases the number of active myosin heads during muscle contraction in fruit flies, leading to the progressive dysfunction of the flight muscles and heart tube.
PubMed ID
30222106
PubMed Central ID
PMC6141230 (PMC) (EuropePMC)
DOI
10.7554/eLife.41178
Related Publication(s)
Research paper

Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy.
Kronert et al., 2018, eLife 7: e38064 [FBrf0240086]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    eLife
    Title
    eLife
    ISBN/ISSN
    2050-084X
    Data From Reference
    Human Disease Models (1)