Sawala, A., Gould, A.P. (2019). Two Negatives Make a Positive for Insulin Secretion and Growth.  Dev. Cell 48(1): 11--12.

FBrf0243016

Note

The confusingly named growth-blocking peptides are nutrient-dependent adipokines that stimulate insulin secretion and boost growth in developing flies. In this issue of Developmental Cell, Meschi et al. (2018) show that these adipose tissue-derived factors regulate insulin secretion by silencing a pair of inhibitory neurons that synapse with insulin-producing cells.