Bonnay, F., Knoblich, J.A. (2020). Prospero Phase-Separating the Way to Neuronal Differentiation.  Dev. Cell 52(3): 251--252.

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Note

Drosophila neural progenitors require the transcriptional repressor Prospero to promptly establish the neuronal fate of their daughter cells to avoid tumorigenesis. In this issue of Developmental Cell, Liu et al. (2020) find that Prospero is mitotically implanted and forms liquid-like droplets mediating HP1a condensation to permanently repress its targets.