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Citation
Hirabayashi, S., Cagan, R. (2020). Systemic Regulation of Local Cell Competition.  Dev. Cell 53(4): 371--372.
FlyBase ID
FBrf0245765
Publication Type
Note
Abstract

Somatic scribble mutant cells are selectively eliminated from the growing Drosophila tissue through cell competition, a tumor-suppressing mechanism that ensures tissue integrity. In this issue of Developmental Cell, Sanaki et al. demonstrate that organismal hyperinsulinemia promotes tumorigenesis by abrogating local cell competition.

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Related Publication(s)
Research paper

Hyperinsulinemia Drives Epithelial Tumorigenesis by Abrogating Cell Competition.
Sanaki et al., 2020, Dev. Cell 53(4): 379--389.e5 [FBrf0245703]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Cell
    Title
    Developmental Cell
    Publication Year
    2001-
    ISBN/ISSN
    1534-5807 1878-1551
    Data From Reference
    Human Disease Models (1)