FB2026_03 , released September 17, 2026
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Citation
Zarnescu, D.C. (2020). Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity.  J. Cell Biol. 219(12): e202010172.
FlyBase ID
FBrf0247421
Publication Type
Note
Abstract
The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
PubMed ID
PubMed Central ID
PMC7716381 (PMC) (EuropePMC)
Related Publication(s)
Research paper

centrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis.
Ryder et al., 2020, J. Cell Biol. 219(12): e202004101 [FBrf0247305]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Cell Biol.
    Title
    Journal of Cell Biology
    Publication Year
    1966-
    ISBN/ISSN
    0021-9525
    Data From Reference