A binding protein regulates myosin-7a dimerization and actin bundle assembly.
Liu et al., 2021, Nat. Commun. 12(1): 563 [
FBrf0247863]
Superresolution characterization of core centriole architecture.
Tian et al., 2021, J. Cell Biol. 220(4): e202005103 [
FBrf0247984]
Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila.
Homeodomain protein Six4 prevents the generation of supernumerary Drosophila type II neuroblasts and premature differentiation of intermediate neural progenitors.
Chen et al., 2021, PLoS Genet. 17(2): e1009371 [
FBrf0248184]
Ago2 protects Drosophila siRNAs and microRNAs from target-directed degradation, even in the absence of 2'-O-methylation.
Kingston and Bartel, 2021, RNA 27(6): 710--724 [
FBrf0249051]
NELF-A controls Drosophila healthspan by regulating heat-shock protein-mediated cellular protection and heterochromatin maintenance.
Ngian et al., 2021, Aging Cell 20(5): e13348 [
FBrf0249056]
Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in Drosophila.
Rosenthal et al., 2021, Proc. Natl. Acad. Sci. U.S.A. 118(23): e2004685118 [
FBrf0249127]
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation.
Liu et al., 2021, Nat. Commun. 12(1): 4173 [
FBrf0249440]
Imaging of In Vitro and In Vivo Neurons in Drosophila Using Stochastic Optical Reconstruction Microscopy.
Inal et al., 2021, Curr Protoc 1(7): e203 [
FBrf0249550]
The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster.
Yoshinari et al., 2021, Nat. Commun. 12(1): 4818 [
FBrf0250203]
Brain adiponectin signaling controls peripheral insulin response in Drosophila.
Arquier et al., 2021, Nat. Commun. 12(1): 5633 [
FBrf0251373]
A Genetic Toolkit for Simultaneous Generation of LexA- and QF-Expressing Clones in Selected Cell Types in Drosophila.
Banzai et al., 2022, Neurosci Insights 17: 26331055211069939 [
FBrf0252480]
Cytonemes coordinate asymmetric signaling and organization in the Drosophila muscle progenitor niche.
Patel et al., 2022, Nat. Commun. 13(1): 1185 [
FBrf0252816]
Septins tune lipid kinase activity and PI(4,5)P2 turnover during G-protein-coupled PLC signalling in vivo.
Kumari et al., 2022, Life Sci Alliance 5(6): e202101293 [
FBrf0252936]
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay.
Cairrão et al., 2022, Nat. Commun. 13(1): 1587 [
FBrf0253014]
Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade.
Schellinger et al., 2022, Curr. Biol. 32(6): 1429--1438.e6 [
FBrf0253018]
Tctp regulates the level and localization of Foxo for cell growth in Drosophila.
Nam et al., 2022, Cell Death Discov. 8(1): 146 [
FBrf0253108]
Juvenile Hormone Membrane Signaling Enhances its Intracellular Signaling Through Phosphorylation of Met and Hsp83.
Gao et al., 2022, Front. Physiol. 13: 872889 [
FBrf0253421]
Single-Cell Atlas of the Drosophila Leg Disc Identifies a Long Non-Coding RNA in Late Development.
Tse et al., 2022, Int. J. Mol. Sci. 23(12): 6796 [
FBrf0253840]
Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo.
van Leeuwen et al., 2022, Cell Rep Methods 2(6): 100235 [
FBrf0253863]
Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides.
Schiemann et al., 2022, Nat. Commun. 13(1): 4420 [
FBrf0254109]
Isoforms of the transcriptional cofactor SIN3 differentially regulate genes necessary for energy metabolism and cell survival.
Mitra et al., 2022, Biochim Biophys Acta Mol Cell Res 1869(10): 119322 [
FBrf0254180]
Optimized protocols for RNA-induced silencing complex assembly and cleavage in cultured Drosophila cells.
Gao et al., 2022, STAR Protoc 3(3): 101596 [
FBrf0254186]
Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus.
Messina et al., 2022, BMC Biol. 20(1): 172 [
FBrf0254229]
NURF301 contributes to gypsy chromatin insulator-mediated nuclear organization.
Chen et al., 2022, Nucleic Acids Res. 50(14): 7906--7924 [
FBrf0254231]
Dual Leucine Zipper Kinase Regulates Dscam Expression through a Noncanonical Function of the Cytoplasmic Poly(A)-Binding Protein.
Singh et al., 2022, J. Neurosci. 42(31): 6007--6019 [
FBrf0254253]
Single amino-acid mutation in a Drosophila melanogaster ribosomal protein: An insight in uL11 transcriptional activity.
Grunchec et al., 2022, PLoS ONE 17(8): e0273198 [
FBrf0254298]
Generation and validation of pX-UASTattB for dose-dependent misexpression studies in Drosophila.
Singh and Kim, 2022, MicroPubl Biol 2022: [
FBrf0254375]
Patched-Related Is Required for Proper Development of Embryonic Drosophila Nervous System.
Bolatto et al., 2022, Front. Neurosci. 16: 920670 [
FBrf0254433]
Imp interacts with Lin28 to regulate adult stem cell proliferation in the Drosophila intestine.
Sreejith et al., 2022, PLoS Genet. 18(9): e1010385 [
FBrf0254532]
Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells.
Deng et al., 2022, PLoS Biol. 20(10): e3001834 [
FBrf0254715]
Profiling RNA at chromatin targets in situ by antibody-targeted tagmentation.
Khyzha et al., 2022, Nat. Methods 19(11): 1383--1392 [
FBrf0254922]
The Drosophila BEAF insulator protein interacts with the polybromo subunit of the PBAP chromatin remodeling complex.
McKowen et al., 2022, G3 (Bethesda) 12(11): jkac223 [
FBrf0254954]
The DEAD-box helicase Hlc regulates basal transcription and chromatin opening of stress-responsive genes.
Jia et al., 2022, Nucleic Acids Res. 50(16): 9175--9189 [
FBrf0255009]
Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila.
Sheffield et al., 2021, G3 (Bethesda) 11(7): jkab116 [
FBrf0255012]
Lysine 27 dimethylation of Drosophila linker histone dH1 contributes to heterochromatin organization independently of H3K9 methylation.
Bernués et al., 2022, Nucleic Acids Res. 50(16): 9212--9225 [
FBrf0255017]
Ptp61F integrates Hippo, TOR, and actomyosin pathways to control three-dimensional organ size.
Liu et al., 2022, Cell Rep. 41(7): 111640 [
FBrf0255060]
Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster.
Gao et al., 2022, Cell Death Differ. 29(12): 2545--2561 [
FBrf0255318]
ChIATAC is an efficient strategy for multi-omics mapping of 3D epigenomes from low-cell inputs.
Chai et al., 2023, Nat. Commun. 14(1): 213 [
FBrf0255480]
Plk4 Is a Novel Substrate of Protein Phosphatase 5.
Ábrahám et al., 2023, Int. J. Mol. Sci. 24(3): 2033 [
FBrf0255743]
Drosophila Me31B is a Dual eIF4E-Interacting Protein.
Layana et al., 2023, J. Mol. Biol. 435(5): 167949 [
FBrf0255814]
CLOCK and TIMELESS regulate rhythmic occupancy of the BRAHMA chromatin-remodeling protein at clock gene promoters.
Tabuloc et al., 2023, PLoS Genet. 19(2): e1010649 [
FBrf0255960]
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye.
Zhao et al., 2023, Dev. Cell 58(5): 416--434.e12 [
FBrf0255981]
Purriato is a conserved small open reading frame gene that interacts with the CASA pathway to regulate muscle homeostasis and epithelial tissue growth in Drosophila.
Pueyo et al., 2023, Front. Cell Dev. Biol. 11: 1117454 [
FBrf0256099]
E2 enzyme Bruce negatively regulates Hippo signaling through POSH-mediated expanded degradation.
Song and Ma, 2023, Cell Death Dis. 14(9): 602 [
FBrf0257532]
Modeling a variant of unknown significance in the Drosophila ortholog of the human cardiogenic gene NKX2.5.
Lovato et al., 2023, Dis. Model Mech. 16(9): dmm050059 [
FBrf0257696]
Scavenger receptor endocytosis controls apical membrane morphogenesis in the Drosophila airways.
Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells.
Wang et al., 2023, Dev. Cell 58(21): 2249--2260.e9 [
FBrf0257985]
Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network.
An EMC-Hpo-Yki axis maintains intestinal homeostasis under physiological and pathological conditions.
Shi et al., 2023, Development 150(24): dev201958 [
FBrf0258337]
IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events.
Fujiwara et al., 2023, Mol. Cell 83(24): 4445--4460.e7 [
FBrf0258341]
Drosophila melanogaster Sting mediates Coxiella burnetii infection by reducing accumulation of reactive oxygen species.
Guzman et al., 2024, Infect. Immun. 92(3): e0056022 [
FBrf0258946]
A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription.
Su et al., 2024, Nucleic Acids Res. 52(7): 3702--3721 [
FBrf0259394]
Cyp6g2 is the major P450 epoxidase responsible for juvenile hormone biosynthesis in Drosophila melanogaster.
The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons.
Lv et al., 2024, Open Biol. 14(7): 230355 [
FBrf0259942]
Minor Spliceosomal 65K/RNPC3 Interacts with ANKRD11 and Mediates HDAC3-Regulated Histone Deacetylation and Transcription.
Li et al., 2024, Adv Sci (Weinh) 11(29): e2307804 [
FBrf0260186]
FMRP cooperates with miRISC components to repress translation and regulate neurite morphogenesis in Drosophila.
Kaul et al., 2024, RNA Biol. 21(1): 11--22 [
FBrf0260272]
Galectins induced from hemocytes bridge phosphatidylserine and N-glycosylated Drpr/CED-1 receptor during dendrite pruning.
Sung et al., 2024, Nat. Commun. 15(1): 7402 [
FBrf0260325]
Generating CRISPR-edited clonal lines of cultured Drosophila S2 cells.
Ryniawec et al., 2024, Biol Methods Protoc 9(1): bpae059 [
FBrf0260333]
Secretion of endoplasmic reticulum protein VAPB/ALS8 requires topological inversion.
Kamemura et al., 2024, Nat. Commun. 15(1): 8777 [
FBrf0260646]
Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover.
EB-SUN, a new microtubule plus-end tracking protein in Drosophila.
Kim et al., 2024, Mol. Biol. Cell 35(12): ar147 [
FBrf0260946]
A noncanonical role of roX RNAs in autosomal epigenetic repression.
Autoregulation of the glial gene reversed polarity in Drosophila.
Santa-maria is a glial phagocytic receptor that acts with SIMU to recognize and engulf apoptotic neurons.
Hilu-Dadia et al., 2025, Cell Rep. 44(1): 115201 [
FBrf0261548]
Drosophila aux orchestrates the phosphorylation-dependent assembly of the lysosomal V-ATPase in glia and contributes to SNCA/α-synuclein degradation.
Zhang et al., 2025, Autophagy 21(5): 1039--1058 [
FBrf0262132]
Transcriptional induction by ecdysone in Drosophila salivary glands involves an increase in chromatin accessibility and acetylation.
Evdokimova et al., 2025, Nucleic Acids Res. 53(7): gkaf284 [
FBrf0262149]
Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development.
Lee et al., 2025, Cell Rep. 44(4): 115495 [
FBrf0262201]
'Mitotic' kinesin-5 is a dynamic brake for axonal growth in Drosophila.
Lu et al., 2025, Development 152(9): dev204424 [
FBrf0262347]
Functional characterization of eicosanoid signaling in Drosophila development.
Fujinaga et al., 2025, PLoS Genet. 21(5): e1011705 [
FBrf0262370]
Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythms and sleep.
Sun et al., 2025, PLoS Biol. 23(5): e3003173 [
FBrf0262553]
A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization.
Gemeinhardt et al., 2025, Mol. Cell 85(11): 2128--2146.e15 [
FBrf0262564]
Upstream open reading frames buffer translational variability during Drosophila evolution and development.
The third intracellular loop of Drosophila Lilipod is required for protein function in vivo and can mediate protein-protein interactions in vitro.
Roy et al., 2025, PLoS ONE 20(6): e0325326 [
FBrf0262581]
Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in Drosophila olfactory receptor neurons.
Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions.
Blanco et al., 2025, Nucleic Acids Res. 53(12): gkaf602 [
FBrf0262829]
Noncanonical action of circadian clock genes controls winter diapause entry via the NuA4/TIP60 complex in Harmonia axyridis.
Gao et al., 2025, Proc. Natl. Acad. Sci. U.S.A. 122(28): e2510550122 [
FBrf0262861]
Identification of novel components of the retinal determination gene network in Drosophila cell lines.
Drewell and Dresch, 2025, Open Biol. 15(7): 250012 [
FBrf0262885]
Conserved biochemical activity and function of phosphatidylinositol 5-phosphate 4-kinase regulates growth and development.
Krishnan et al., 2025, J. Cell Sci. 138(13): jcs263881 [
FBrf0262908]
A U3 snoRNA is required for the regulation of chromatin dynamics and antiviral response in Drosophila melanogaster.
Jain et al., 2025, Nucleic Acids Res. 53(14): gkaf715 [
FBrf0263077]
20E-induced Kr-h1 expression facilitates developmental transitions depending on chromosome accessibility of BR-C enhancers.
Long et al., 2025, Proc. Natl. Acad. Sci. U.S.A. 122(32): e2509608122 [
FBrf0263106]
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling.
Santos et al., 2025, Nat. Commun. 16(1): 7523 [
FBrf0263179]
The secreted Nimrod protein NimB1 negatively regulates early steps of apoptotic cell phagocytosis in Drosophila.
Dolgikh et al., 2025, Development 152(16): dev204919 [
FBrf0263186]
Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division.
Hao et al., 2020, Genome Res. 30(11): 1570--1582 [
FBrf0247182]
Repression of interrupted and intact rDNA by the SUMO pathway in Drosophila melanogaster.
Activation-induced substrate engagement in ERK signaling.
Paul et al., 2020, Mol. Biol. Cell 31(4): 235--243 [
FBrf0247520]
Patterning and growth control in vivo by an engineered GFP gradient.
Stapornwongkul et al., 2020, Science 370(6514): 321--327 [
FBrf0246949]
A Cell Adhesion-Based Reconstitution Method for Studying Cell Polarity.
Johnston, 2020, Front. Cell Dev. Biol. 8: 598492 [
FBrf0247212]
Loss of the spectraplakin gene Short stop induces a DNA damage response in Drosophila epithelia.
Dewey et al., 2020, Sci. Rep. 10(1): 20165 [
FBrf0247310]
Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation.
Schauer et al., 2017, EMBO Rep. 18(10): 1854--1868 [
FBrf0243679]
Seizure suppression through manipulating splicing of a voltage-gated sodium channel.
