FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Keene, A.C., Joiner, W.J. (2015). Neurodegeneration: paying it off with sleep.  Curr. Biol. 25(6): R234--RR236.
FlyBase ID
FBrf0250276
Publication Type
Note
Abstract
A new study in fruit flies suggests modulation of neural activity links sleep and Alzheimer's disease. Both sleep loss and amyloid beta increase neural excitability, which reinforces the accumulation of amyloid beta and shortens lifespan.
PubMed ID
25784043
PubMed Central ID
PMC4381801 (PMC) (EuropePMC)
DOI
10.1016/j.cub.2015.02.003
Related Publication(s)
Research paper

Sleep interacts with aβ to modulate intrinsic neuronal excitability.
Tabuchi et al., 2015, Curr. Biol. 25(6): 702--712 [FBrf0227863]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference