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Citation
Chen, T., Cao, X. (2021). cGAS-like receptors: ancient catchers of viral nucleic acids.  Trends Immunol. 42(11): 945--947.
FlyBase ID
FBrf0251715
Publication Type
Note
Abstract
Living organisms have evolved conserved 'catchers' for detecting and handling molecular patterns from invading viruses. Slavik et al. and Holleufer et al. recently identified cyclic GMP-AMP (cGAMP) synthase (cGAS)-like receptors that detect double-stranded viral RNA in Drosophila. cGAS-like receptors constitute a new expanding family of pattern recognition receptors (PRRs) for viral nucleic acids.
PubMed ID
34635392
PubMed Central ID
DOI
10.1016/j.it.2021.09.012
Related Publication(s)
Research paper

cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Slavik et al., 2021, Nature 597(7874): 109--113 [FBrf0250905]

Two cGAS-like receptors induce antiviral immunity in Drosophila.
Holleufer et al., 2021, Nature 597(7874): 114--118 [FBrf0250901]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Immunol.
    Title
    Trends in Immunology
    Publication Year
    2001-
    ISBN/ISSN
    1471-4906
    Data From Reference
    Gene Groups (1)