FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Fudenberg, G., Nora, E.P. (2021). Embryogenesis without CTCF in flies and vertebrates.  Nat. Struct. Mol. Biol. 28(10): 774--776.
FlyBase ID
FBrf0251938
Publication Type
Note
Abstract
CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails embryogenesis in zebrafish and Drosophila melanogaster, revealing contrasting effects across species.
PubMed ID
34580493
PubMed Central ID
DOI
10.1038/s41594-021-00662-x
Related Publication(s)
Research paper

CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions.
Kaushal et al., 2021, Nat. Commun. 12(1): 1011 [FBrf0248103]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Struct. Mol. Biol.
    Title
    Nature Structural and Molecular Biology
    Publication Year
    2004-
    ISBN/ISSN
    1545-9993 1545-9985
    Data From Reference