FB2026_03 , released September 17, 2026
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Citation
Stow, J.L., Sweet, M.J. (2023). Macrophage Nrf 2 the rescue.  J. Cell Biol. 222(6): e202305036.
FlyBase ID
FBrf0256564
Publication Type
Note
Abstract
The exuberant phagocytosis of apoptotic cell corpses by macrophages in Drosophila embryos creates highly oxidative environments. Stow and Sweet discuss work from Clemente and Weavers (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202203062) showing for the first time how macrophage Nrf2 is primed to help sustain immune function and mitigate bystander oxidative damage.
PubMed ID
PubMed Central ID
PMC10203544 (PMC) (EuropePMC)
Related Publication(s)
Research paper

A PI3K-calcium-Nox axis primes leukocyte Nrf2 to boost immune resilience and limit collateral damage.
Clemente and Weavers, 2023, J. Cell Biol. 222(6): e202203062 [FBrf0256201]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Cell Biol.
    Title
    Journal of Cell Biology
    Publication Year
    1966-
    ISBN/ISSN
    0021-9525
    Data From Reference