FB2026_02 , released June 18, 2026
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Kogenaru, M. (2023.9.7). P{tubP-GAL80.1xDHFR22-T2A-mCh} construct and insertion from M. Kogenaru. 
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FBrf0257559
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Personal communication to FlyBase
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The following information accompanied stocks donated to the Bloomington Drosophila Stock Center by Manjunatha Kogenaru, Imperial College London, South Kensington Campus.
P{tubP-GAL80.1xDHFR22-T2A-mCh} carries a tubulin promoter driving GAL80 fused to the destabilizing domain, DHFR22, followed by a self-cleaving T2A linker and mCherry. In the absence of trimethoprim (TMP), the DHFR22 domain destabilizes GAL80. In the presence of TMP, GAL80 is stabilized and can inhibit GAL4.
P{tubP-GAL80.1xDHFR22-T2A-mCh}JB37B is a viable insertion on the second chromosome into JK37B (FBti0102077).
P{tubP-GAL80.1xDHFR22-T2A-mCh}JB89B is an insertion on the third chromosome into JB89B (FBti0102080).
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Related Publication(s)
Research paper

A drug stabilizable GAL80[ds] for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila.
Kogenaru et al., 2024, Sci. Rep. 14(1): 5893 [FBrf0259011]

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    English
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    Alleles (1)
    Genes (1)
    Natural transposons (1)
    Insertions (4)
    Experimental Tools (2)
    Transgenic Constructs (1)