Bi, P., Geisbrecht, E.R. (2024). Cell fusion: Inter-organ tissue communication promotes a union between myoblasts.  Curr. Biol. 34(9): R343--RR345.

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Repeated rounds of fusion between apposing myoblasts allow muscles to become multinucleated. New research finds that myoblasts undergoing fusion in the Drosophila embryo respond to hormone signaling from a nearby tissue, resulting in the activation of a myoblast-specific gene necessary for the fusion process.