FB2026_03 , released September 17, 2026
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González-Reyes, A. (2025.5.16). Location data for Smu1 alleles. 
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FBrf0262441
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Personal communication to FlyBase
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The Smu11 allele bears an 11-base pair deletion (...AGCAGTATCTGAAGGAGTCCAACC-11 deleted nucleotides-CTGCAAACGTTACAGGTtagTACTT...) that gives rise to an early stop codon (lower case). The truncated Smu11 protein only contains the first 22 original N-terminal amino acids followed by 6 ectopic ones. The 11 deleted bases have the following coordinates:  3R:18980700..18980710 .
The Smu12 allele contains a 12-base deletion (...GCAGTATCTGAAGGAGTCCAACCT-12 deleted nucleotides-GCAAACGTTACAGGTTAGTACTTG...) that removes 4 amino acids (M24-K25-T26-L27) from the LISH domain but preserves the rest of the open reading frame. The 12 deleted bases have the following coordinates:  3R:18980698..18980709 .
Both alleles were generated using CRISPR. See FBrf0261882 Even-Ros et al., 2025, Nat. Commun. 16(1): 2596 for details.
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Research paper

Drosophila ovarian stem cell niche ageing involves coordinated changes in transcription and alternative splicing.
Even-Ros et al., 2025, Nat. Commun. 16(1): 2596 [FBrf0261882]

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    English
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    Alleles (2)
    Genes (1)