FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Popodi, E.M., Parks, A.L., Rusch, D. (2025.8.28). l(3)CHc is allelic to CG12290. 
FlyBase ID
FBrf0263316
Publication Type
Personal communication to FlyBase
Abstract
PubMed ID
PubMed Central ID
Text of Personal Communication
The Bloomington Drosophila Stock Center has identified l(3)CHc1 (FBal0195763) and l(3)CHc2 (FBal0195764) as alleles of the CG12290 gene.  l(3)CHc is group 5 in Jiang and Crews, 2006 (FBrf0193980, see also FBrf0199131).  Both l(3)CHc alleles are homozygous lethal and fail to complement Df(3R)Exel6204 (also shown by Jiang and Crews, 2006, FBrf0193980; RRID:BDSC_7683) and Mi{MIC}CG12290MI15247 (RRID:BDSC_61005).  Whole genome sequencing reveals the following mutation in the CG12290 gene in l(3)CHc2:
l(3)CHc2 = CG12290CHc2, deletion of CTGT at  3R:26232013..26232016  followed by GGC instead of TGG. The result is a frameshift following P436 with 7 aa (GALLRRI) of frameshifted protein translated before hitting a stop codon.
l(3)CHc1 = CG12290CHc1 based on genetic evidence; no mutations were found in CG12290 coding regions (non-coding regions were not analyzed).
DOI
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Abbreviation
    Title
    ISBN/ISSN
    Data From Reference
    Aberrations (1)
    Alleles (3)
    Genes (1)
    Insertions (1)