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General Information
Symbol
Dhyd\Minos
Species
D. hydei
Feature type
FlyBase ID
FBte0000026
Sequences and Components
Complete element (bp)

1775

Terminal repeat (bp)

255

Component genes
Sequence Accessions
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Sequence Ontology (SO)
Insertions and Copy Number
Copy number and comments

to 30

Target Site Duplication
Size (bp)

0 or 1

Orthologs
Comments

Mi{ET1} insertions in D. melanogaster are over-represented in both testis-specific and all other loci within underreplicated regions of the genome (URs) compared to flanks; this pattern is the opposite of that observed with insertions of P-element and Tni\piggyBac transgenic constructs.

A defective Dhyd\Minos transposon that is inserted into the D.melanogaster genome is stable in the absence of Dhyd\Minos\T but is mobilised at relatively high frequencies in the presence of transposase. Transposase can induce transposition of defective Dhyd\Minos to a new location. Analysis of structures remaining after excision suggests the breaks can be repaired by two alternative mechanisms: gap repair or ligation repair.

Precise excisions can be recovered only from heterozygotes, and not from hemi- or homozygotes. Footprints of 6 nucleotides are generally left in excisions from hemi- or homozygotes and are left at a frequency of 25% in excisions from heterozygotes. The gap left after Dhyd\Minos excision might be repaired by an alternative mechanism not involving gene conversion and the structure of the repaired donor sites might, in some way, reflect the mechanism of action of Dhyd\Minos transposase.

Dhyd\Minos elements actively transpose in the germ line, and are characterised by a striking degree of sequence and size homogeneity. Elements insert in a TA nucleotide that is probably duplicated during the process.

A Dhyd\Minos element has been cloned and sequenced.

Other Information
Etymology
External Crossreferences and Linkouts ( 4 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (7)
Reported As
Secondary FlyBase IDs
  • FBgn0004585
  • FBtp0011478
  • FBgn0010242
References (75)