FB2026_03 , released September 17, 2026
Recombinant Construct: M{UAS-Khc.N262S}
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General Information
Symbol
M{UAS-Khc.N262S}
FlyBase ID
FBtp0083006
Feature type
transgenic_transposable_element
Component Allele(s)
KhcN262S.UAS
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele KhcN262S.UAS
Transgenic product class
dominant_negative_variant
(Füger et al., 2012)
missense_variant
(Füger et al., 2012)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Khc
Description

UAS regulatory sequences drive expression of the Khc SD02406 cDNA, which has been mutated to contain the amino acid replacement N262S (equivalent to the N256S mutation in the KIF5A gene which results in hereditary spastic paraplegia in humans).

(Füger et al., 2012)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
M{UAS-Khc.N262S}
(FlyBase, 1992-)
UAS-khcN262S
(Füger et al., 2012)
Secondary FlyBase IDs
    References (3)