FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Recombinant Construct: P{Ubi-tkv-TIPF}
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General Information
Symbol
P{Ubi-tkv-TIPF}
FlyBase ID
FBtp0093189
Feature type
transgenic_transposable_element
Component Allele(s)
tkvTIPF.Ubi-p63E
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele tkvTIPF.Ubi-p63E
Transgenic product class
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
tkv
Description

Ubi-p63E regulatory sequences drive expression of 'TIPF', a sensor that can be used to assay tkv activation. It consists of tkv isoform-D coding sequences fused to the conformation-sensitive circularly permutated yellow fluorescent protein (cpYFP) and FKBP12 (a motif that binds to the unphosphorylated glycine-serine rich domain of inactive type I BMP receptors). Activation of tkv displaces the FKBP12 motif, allowing cpYFP to adopt a fluorescent conformation.

(Michel et al., 2011)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{Ubi-tkv-TIPF}
(FlyBase, 1992-)
ubi::TIPF
(Michel et al., 2011)
Secondary FlyBase IDs
    References (3)