FB2026_03 , released September 17, 2026
Recombinant Construct: PBac{Sply-HA.S335I}
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General Information
Symbol
PBac{Sply-HA.S335I}
FlyBase ID
FBtp0117368
Feature type
transgenic_transposable_element
Component Allele(s)
SplyS335I.Tag:HA
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele SplyS335I.Tag:HA
Transgenic product class
missense_variant
(Lovric et al., 2017)
Component
Use(s)
Regulatory region(s)
Sply
Encoded product / tool
Sply
Tagged with
Tag:HA
Description

4kb genomic fragment that contains the Sply gene, including 491bp of upstream regulatory sequences and the 3'UTR. The coding region has been mutated to contain the S335I amino acid replacement, which is equivalent to the disease-associated S346I mutation in the orthologous human SGPL1 gene. A Tag:HA tag has been inserted at the C-terminal end of the Sply open reading frame.

(Lovric et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PBac{Sply-HA.S335I}
(FlyBase, 1992-)
Sply HA S335I
(Lovric et al., 2017)
Secondary FlyBase IDs
    References (3)