Encodes the SREBP protein with C-terminal tags. SREBP protein localizes to the Golgi and the N-terminus is cleaved to produce a transcription factor. The tagged protein remains associated with the Golgi. The transcription factor fragment is untagged.
Genomic fragment including the SREBP gene, from BAC clone CH322-183B11. A sfGFP-Tag:FLAG-Tag:CS(PSP)-Tag:CS(TEVp)-Tag:BLRP tag cassette has been introduced at the C-terminal end of the SREBP gene, such that isoforms A, B, C and D are tagged.