FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-LAPD}
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General Information
Symbol
P{UAS-LAPD}
FlyBase ID
FBtp0130588
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\PDE2A::Drad\BphPLAPD.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\PDE2A::Drad\BphPLAPD.UAS
Transgenic product class
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\PDE2A::Drad\BphP
Description

UAS regulatory sequences drive expression of 'LAPD', a light-regulated phosphodiesterase. LAPD consists of the photosensor module (the PAS-GAF-PHY domains) of Deinococcus radiodurans bacterial phytochrome (Drad\BphP) fused to the effector module (amino acid residues 555-941) of Hsap\PDE2A. The photosensor module requires a biliverdin chromophore which is incorporated autonomously. Exposure to red light (690nm) activates hydrolysis of cAMP and cGMP, while far-red light (850nm) can be used to down-regulate activity (PMID:24889611).

(Schumacher et al., 2016)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
78813
w*; P{UAS-LAPD}3
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P{UAS-LAPD}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (4)