FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-hADD3.E659Q.V5}
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General Information
Symbol
P{UAS-hADD3.E659Q.V5}
FlyBase ID
FBtp0131992
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\ADD3E659Q.UAS.Tag:V5
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\ADD3E659Q.UAS.Tag:V5
Transgenic product class
missense_variant
(Gonçalves et al., 2018)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ADD3
Tagged with
Tag:V5
Description

UASt regulatory sequences drive expression of a Hsap\ADD3 cDNA (IMAGE clone 6649991) that has been mutated to contain the E659Q amino acid variant (a potentially damaging mutation found to be segregating with the disease phenotype in a family with intellectual disability and microcephaly). The coding sequence is tagged at the N-terminal end with Tag:V5.

(Gonçalves et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Add-γ E659Q
(Gonçalves et al., 2018)
P{UAS-hADD3.E659Q.V5}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)