FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-Syt1.I426K}
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General Information
Symbol
P{UAS-Syt1.I426K}
FlyBase ID
FBtp0134206
Feature type
transgenic_transposable_element
Component Allele(s)
Syt1I426K.UAS.Tag:MYC
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Syt1I426K.UAS.Tag:MYC
Transgenic product class
missense_variant
(Montes-Chinea et al., 2018)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Syt1
Tagged with
Tag:MYC
Description

UAS regulates expression of mutant Syt1 bearing a I426K mutation, equivalent to the missense I371 mutation in human 'SYT2' that causes distal hereditary motor neuropathy and presynaptic neuromuscular junction (NMJ) transmission dysfunction. The construct has an N-terminal Tag:MYC tag.

(Montes-Chinea et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
I426K SYT
(Montes-Chinea et al., 2018)
P{UAS-Syt1.I426K}
(FlyBase, 1992-)
SYT1 I426K
(Montes-Chinea et al., 2018)
Secondary FlyBase IDs
    References (3)