FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-mtRosella}
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General Information
Symbol
P{UAS-mtRosella}
FlyBase ID
FBtp0141244
Feature type
transgenic_transposable_element
Component Allele(s)
Avic\GFPmtRosella.UAS
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Avic\GFPmtRosella.UAS
Transgenic product class
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Avic\GFP
Tagged with
Tag:Mito(Unk)
Description

UAS regulatory sequences drive expression of 'mtRosella' (PMID:24530295), which functions as a biosensor for the mitophagy process in vivo. The construct consists of Rosella (a pH-sensitive GFP fused to a RFP(Unk)) fused to a mitochondrial targeting sequence (Tag:Mito(Unk)); under normal conditions, the green and red signals overlap in mitochondria, whereas upon mitophagy mtRosella is transferred to the vacuole where the green signal is lost due to the acidic pH.

(Edenharter et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-mtRosella}
(FlyBase, 1992-)
UAS-mtRosella
(Edenharter et al., 2018)
Secondary FlyBase IDs
    References (3)