FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-rl.D334N.K}
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General Information
Symbol
P{UAS-rl.D334N.K}
FlyBase ID
FBtp0141325
Feature type
transgenic_transposable_element
Component Allele(s)
rlD334N.UAS.cKa
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele rlD334N.UAS.cKa
Transgenic product class
gain_of_function_variant
(Kushnir et al., 2020)
missense_variant
(Kushnir et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
rl
Description

UASt regulates expression of rl containing the "sevenmaker" gain-of-function mutation (D334N) - the equivalent mutation is found in cancer patients (D321N in human ERK2).

(Kushnir et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-rl.D334N.K}
(FlyBase, 1992-)
RolledD334N
(Kushnir et al., 2020)
Secondary FlyBase IDs
    References (3)