FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hCFTR.ΔF508.HA}
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General Information
Symbol
P{UAS-hCFTR.ΔF508.HA}
FlyBase ID
FBtp0143738
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\CFTRΔF508.UAS.Tag:HA
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\CFTRΔF508.UAS.Tag:HA
Transgenic product class
inframe_deletion
(Kim et al., 2020)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\CFTR
Tagged with
Tag:HA
Description

UAS and a core promoter regulates expression of Tag:HA-tagged Hsap\CFTR carrying an in-frame deletion of phenylalanine 508, a mutation that occurs in more than 70% of Cystic Fibrosis patients and which affects Hsap\CFTR protein transport.

(Kim et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hCFTR.ΔF508.HA}
(FlyBase, 1992-)
hCFTRΔF508
(Kim et al., 2020)
Secondary FlyBase IDs
    References (3)